114 Conversely, cancer cells have no way to normalize their internal pH, where normal cells are relatively unaffected by high concentrations of alkalizing minerals. However cancer cells take up primarily two elements: glucose and potassium. In practical application, then, it is necessary to find a way to guide alkalizing elements - such as cesium, germanium or rubidium - into cancer cells, without impacting normal cells. It turns out this can be done using a transport agent that penetrates the bone/blood barriers, then relying on the normal uptake of alkalizing elements that follow the potassium pathway. Cancer cells appear to have preferential uptake of cesium chloride in particular, but also take up germanium, rubidium, selenium, etc. all through the potassium pathway.
There is a compound that is frequently applied to the skin by arthritis sufferers for relief of inflammation, used in brain surgery to relieve intracranial pressure and topically used in sports medicine and veterinary medicine, also for reducing inflammation. This compound is called DMSO and it is formed in the slurry created from soaking wood chips in water that is a bi-product of the paper making industry. Folklore has it that workers in the paper making industry were observed to have their hands in water continuously, but they never developed arthritis and had rapidly healing skin and strong nails. Experimentation with DMSO as a medical treatment began in the 1800's and continues to the present day. DMSO is medically approved in the United States only for the treatment of interstitial cystitis, a type of inflammation of the bladder
112 In the 1880's, Louis Pasteur published his work on cellular aerobic respiration and glycolysis. In 1931, Otto Warburg won the Nobel Prize for his work on the metabolism of tumors and the respiration of cells, which was later summarized in his 1956 paper, On the Origin of Cancer Cells. His work on cancer expanded upon Pasteur's findings and described respiratory insufficiency and a cellular metabolism of glucose fermentation as the primary trigger for cancer progression.
Warburg's conclusions on cancer were much discussed in scientific circles, as they are academically elegant, but were not accepted by most members of the scientific community engaged in cancer research. Most cancer researchers in the late 1950's believed that the anaerobic metabolism of cancer cells and their accompanying output of lactic acid was a side effect or an adjunct effect of cancer, not a cause. Cancer research since the 1960's has focused primarily on genetic aberrations as causative for cancer, and has ignored the body of research on cancer pH and its implications for therapeutic approaches. Warburg's work was a catalyst for yet another research effort on the nature of cancer cells, beginning in the 1930's. A. Keith Brewer, PhD (physicist) performed experiments on the relationship between energized, oxygenated cell membrane and elemental uptake, vs. cellular membranes in an unenergized state such as cancer cells exhibit. He wrote a number of papers discussing the cellular mechanisms of cancer cells and the changes in metabolism induced or indicated by the lack of or presence of oxygen in combination with other elements, particularly potassium and calcium. He noted that cancer cells share one characteristic no matter what type of cancer: they have lost their pH control mechanism.